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It is with great sadness that we report the passing of Dr. Naguib. He was instrumental in the research and development of NTRX-07. He will be greatly missed by us as we strive to carry his work and vision forward to offer new treatments for neurodegenerative diseases and neuropathic pain.


Mohamed Naguib Attala, MD, died Feb. 16, 2020. He was 67.


Dr. Naguib joined Cleveland Clinic as a staff anesthesiologist in the Department of General Anesthesiology in 2010. He was also a Professor of Anesthesiology at Cleveland Clinic Lerner College of Medicine of Case Western Reserve University.


Dr. Naguib was nationally recognized for his pioneering scholarly work on neuromuscular monitoring His findings were translated by investigators in many publications.


He was the principal author or co-author of 130 peer-reviewed journal articles, 25 book chapters (including the premier Miller’s Textbook of Anesthesia) and 150 abstracts. He also served on the editorial board of numerous anesthesia journals and was a past president of the International Society for Anesthesia Pharmacology.


Dr. Naguib is also celebrated for his work as a NIH-funded basic science researcher and co-founder of NeuroTherapia, which is developing a novel therapy for neuropathic pain and Alzheimer’s Disease based on his research on the mechanisms of neuroinflammation. Dr. Naguib's major research focus has centered on cannabinoid receptor modulators and drug development. His research on epigenetic regulation of genes involved in cognition, and his recent data (including findings published in Nature Neuroscience), have contributed to an understanding of epigenetic and molecular mechanisms involved in the modulation of learning and memory process in Alzheimer's Disease. Dr. Naguib was most recently involved with a development program for NTRX-07, a small novel neuroprotective molecule which acts on the cannabinoid type 2 receptors on microglia in the CNS.


Prior to joining Cleveland Clinic, Dr. Naguib was a Professor of Anesthesiology at The University of Texas MD Anderson Cancer Center in Houston.


“It is with deep sadness that I share with you that Mohamed has passed away. Mohamed was a nationally and internationally renowned anesthesiologist who exemplified the career of a successful academic physician. To us, he was a colleague, a friend, and a mentor. Our thoughts and prayers go out to his family,” says Maged Argalious, MD, Chair of the Department of General Anesthesiology.


Dr. Naguib is survived by his wife and three daughters.

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